iTunes could not connect to the iPhone because an invalid response was received from the device

The immediate solution for this is to update your Machine's iTunes version to 12.5.1, in case, it requires an updated OS X / macOS version to run. Exceptions are  Windows 7,8, 10.

You are now required to upgrade. You have to buy a new computer to sync to that phone, or use BootCamp and install a Windows release.

You're not the first to come here with this situation and probably not the last.

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